Education, Training and Professional Registration
Guidelines
Laboratory Management, Staffing and Professional Practice
Quality Management and Laboratory Accreditation
Standardization of Laboratory Procedures
The following articles have been published by EFCC (and its predecessor organizations EC4 and FESCC) committees and working groups.
Articles published in Clin Chem Lab Med since 1998 may be downloaded from the CCLM website.
Education, Training and Professional Registration
The European Register of Specialists in Clinical Chemistry and Laboratory Medicine: Code of Conduct, Version 2 – 2008
McMurray J, Zerah S, Hallworth M, Koeller U, Blaton V, Tzatchev K, Charilaou C, Racek J, Johnsen A, Tomberg K, Harmoinen A, Baum H, Rizos D, Kappelmayer J, O’Mullane J, Nubile G, Pupure S, Kucinskiene Z, Opp M, Huisman W, Solnica B, Reguengo H, Grigore C, Spanár J, Strakl G, Queralto J, Wallinder H, Schuff-Werner P
Clin Chem Lab Med. 2009; 47(3): 372-375
PMID: 19191737
The EC4 European Register of Specialists in Clinical Chemistry and Laboratory Medicine
Pazzagli M, McMurray J, Zerah S
Clin Chim Acta. 2008 Jul 1;393(1):27-30
PMID: 18420033
EC4 European Syllabus for Post-Graduate Training in Clinical Chemistry and Laboratory Medicine: version 3 – 2005
Zerah S, McMurray J, Bousquet B, Baum H, Beastall GH, Blaton V, Cals MJ, Duchassaing D, Gaudeau-Toussaint MF, Harmoinen A, Hoffmann H, Jansen RT, Kenny D, Kohse KP, Köller U, Gobert JG, Linget C, Lund E, Nubile G, Opp M, Pazzagli M, Pinon G, Queralto JM, Reguengo H, Rizos D, Szekeres T, Vidaud M, Wallinder H; European Communities of Clinical Chemistry, EC4 Register Commission
Clin Chem Lab Med. 2006;44(1):110-20
PMID: 16375596
The European Register for Specialists in Clinical Chemistry and Laboratory Medicine: Code of Conduct
Sanders G, Opp M, McMurray J, Koeller U, Blaton V, Lund E, Harmoinen A, Zerah S, Baum H, Rizos D, Kenny D, Pazzagli M, Hoffman H, Reguengo H, Queraltó JM, Wallinder H, Jansen R, Hallworth M, Schuff-Werner P; European Communities Confederation of Clinical Chemistry and Laboratory Medicine (EC4)
Clin Chem Lab Med. 2004 May;42(5):563-5
PMID: 15202796
The European Register for Specialists in Clinical Chemistry and Laboratory Medicine: guide to the Register Version 2-2003 and procedure for re-registration
Gurr E, Koller U, Blaton V, Lund E, Harmoinen A, Zerah S, Rizos D, Kenny D, Pazzagli M, Opp M, Willems H, Reguengo H, Queraltó J, Wallinder H, McMurray J, Jansen R, Parviainen M, Beastall G, Kohse KP; European Communities Confederation of Clinical Chemistry and Laboratory Medicine (EC4), EC4 Register Commission
Clin Chem Lab Med. 2003 Feb;41(2):238-47
PMID: 12667013
The EC4 register of European clinical chemists and EC4 activities
Jansen RT
Clin Chim Acta. 2002 May 21;319(2):143-8
PMID: 11955491
Accreditation and postgraduate training in European countries: an FESCC survey. Federation of European Societies of Clinical Chemistry
Blaton V
Clin Chim Acta. 2001 Jul 20;309(2):115-20
PMID: 11438289
FESCC survey on accreditation and post-graduate training in clinical chemistry in European countries. Federation of European Societies of Clinical Chemistry
Rossier M, Blaton V, Franzini C, Queralto JM, Palicka V
Clin Chem Lab Med. 2000 Apr;38(4):371-6
PMID: 10928659
EC4 European syllabus for post-graduate training in clinical chemistry. Version 2—1999. European Communities Confederation of Clinical Chemistry, EC4 Register Commission
Bousquet B, Brombacher PJ, Zérah S, Beastall GH, Blaton V, Charret J, Gurr E, Halpern M, Jansen RT, Kenny D, Kohse KP, Köller U, Lund E, McMurray J, Opp M, Parviainen M, Pazzagli M, Queraltó JM, Sotiropoulou G, Sanders GT
Clin Chem Lab Med. 1999 Nov-Dec;37(11-12):1119-27
PMID: 10726821
European Communities Confederation of Clinical Chemistry Guide to the EC4 register: European Clinical Chemist.
[No authors listed]
Eur J Clin Chem Clin Biochem. 1997 Oct;35(10):797-803
PMID: 9368801
The European Register for Clinical Chemists. (European Communities Confederation of Clinical Chemistry, Working Group on Registration)
Sanders GT, Kelly AM, Breuer J, Kohse KP, Mocarelli P, Sachs C
Eur J Clin Chem Clin Biochem. 1997 Oct;35(10):795-6
PMID: 9368800
Recent activities of EC4 in the harmonization of clinical chemistry in the European Union
Sanders GT, Jansen RT, Beastall G, Gurr E, Kenny D, Kohse KP, Zérah S
Clin Chem Lab Med. 1999 Apr;37(4):477-80
PMID: 10369121
The role of European Communities Confederation of Clinical Chemistry (EC4) in the harmonisation of clinical chemistry in the European Union
Sanders GT, Kelly AM, Breuer J, Mocarelli P
Eur J Clin Chem Clin Biochem. 1995 Dec;33(12):947-8
PMID: 8845427
Clinical chemistry in the European community. Development of international regulations on education, recognition and free exchange of professionals. European Communities Clinical Chemistry Committee
Brombacher PJ, Breuer J, Sanders GT
J Clin Chem Clin Biochem. 1990 Apr;28(4):189-91
PMID: 2358787
Guidelines
A pilot survey of the use and implementation of cardiac markers in acute coronary syndrome and heart failure across Europe. The CARdiac MArker Guideline Uptake in Europe (CARMAGUE) study
Pulkki K, Suvisaari J, Collinson P, Ravkilde J, Stavljenic-Rukavina A, Hammerer-Lercher A, Baum H, van Dieijen-Visser MP, Laitinen P
Clin Chem Lab Med. 2009;47(2):227-34
PMID: 19099527
How well do laboratories follow guidelines on cardiac markers? The cardiac marker guideline uptake in Europe study
Collinson P, Pulkki K, Suvisaari J, Ravkilde J, Stavljenic-Rukavina A, Hammerer-Lercher A, Baum H, van Dieijen-Visser MP, Laitinen PH
Clin Chem. 2008 Feb;54(2):448-9
PMID: 18223141
Laboratory Management, Staffing and Professional Practice
A guide to defining the competence required of a consultant in clinical chemistry and laboratory medicine
Beastall G, Kenny D, Laitinen P, ten Kate J
Clin Chem Lab Med. 2005 Jun;43(6):654-9
PMID: 16006263
The number of consultant clinical chemists in the 15-nation European Union
Smit E, Beastall G, Bjorses U-M, Candito M, Fiorentini P
Clin Chem Lab Med. 2005 Mar; 43(3): 335-41
PMID: 15843242
The management of clinical laboratories in Europe: a FESCC survey. Forum of the European Societies of Clinical Chemistry and Laboratory Medicine
de Kieviet W, Blaton V, Kovacs GL, Palicka V, Pulkki K
Clin Chem Lab Med. 2002 Mar;40(3):312-9
PMID: 12005224
The Practise of Clinical Chemistry in the European Union
Sanders GTB, Beastall GH, Kohse KP, Zerah S, Jansen R, Köller U, Blaton V, Lund E, Parviainen M, Charret J, Gurr E, Nicholou H, Kenny D, Pazzagli M, Opp M, Willems H, do Carmo Martins M, Queralto J, Landin B, Yu A, McMurray J
Clin Chem Lab Med. 2002 Feb;40(2):196-204
PMID: 11939495
Quality Management and Laboratory Accreditation
Addendum to the recent report of EC4 on the accreditation of medical laboratories in the European Union
Haeckel R
Clin Chem Lab Med. 2007;45(11):1564; author reply 1565
PMID: 17970712
Accreditation of medical laboratories in the European Union
Huisman W, Horvath AR, Burnett D, Blaton V, Czikkely R, Jansen RT, Kallner A, Kenny D, Mesko P, Plebani M, Queralto J, Schumann G, Sprongl L, Vitkus D, Wallinder H, Zerah S
Clin Chem Lab Med. 2007;45(2):268-75
PMID: 17311523
EQUAL-qual: A European Program for External Quality Assessment of Genomic DNA Extraction and PCR Amplification
Orlando C, Verderio P, Maatman R, Dannberg J, Ramsden S, Neumaier M, Taruscio D, Falbo V, Jansen R, Casini-Raggi C, Malentacchi F, Marubini E, Pizzamiglio S, Vernelen K, Libeer J-C, Palicka V, Pazzagli M
Clin Chem. 2007; 53(7): 1349-57
PMID: 17582151
The EC4 quality manual model
Queraltó JM
Clin Chim Acta. 2001 Jul 20;309(2):127-36
PMID: 11438291
European Communities Confederation of Clinical Chemistry Working Group on Accreditation: past, present and future
Huisman W
Clin Chim Acta. 2001 Jul 20;309(2):111-4
PMID: 11438288
Usefulness of EC4 essential criteria for quality systems of medical laboratories as guideline to the ISO 15189 and ISO 17025 documents. European Community Confederation of Clinical Chemistry (EC4) Working Group on Harmonisation of Quality Systems and Accreditation
Jansen RT, Kenny D, Blaton V, Burnett D, Huisman W, Plebani M, Queraltó JM, Zérah S, van Lieshout J
Clin Chem Lab Med. 2000 Oct;38(10):1057-64
PMID: 11140624
Additional Essential Criteria for Quality Systems of Medical Laboratories. European Community Confederation of Clinical Chemistry (EC4) Working Group on Harmonisation of Quality Systems and Accreditation
Jansen RT, Blaton V, Burnett D, Huisman W, Queraltó JM, Zérah S, Allman B
Clin Chem Lab Med. 1998 Apr;36(4):249-52
PMID: 9638352
Essential criteria for quality systems in medical laboratories
Jansen RT, Blaton V, Burnett D, Huisman W, Queraltó JM, Zérah S, Allman B
Eur J Clin Chem Clin Biochem. 1997 Feb;35(2):121-2
PMID: 9056756
Quality and accreditation systems in clinical biochemistry in the European Union
Jansen RT, Blaton V, Burnett D, Queraltó JM, Huisman W
Eur J Clin Chem Clin Biochem. 1995 Jun;33(6):393-8
PMID: 7578620
Standardization of Laboratory Procedures
Trueness verification of actual creatinine assays in the European market demonstrates a disappointing variability that needs substantial improvement. An international study in the framework of the EC4 creatinine standardization working group
Delanghe JR, Cobbaert C, Galteau MM, Harmoinen A, Jansen R, Kruse R, Laitinen P, Thienpont LM, Wuyts B, Weykamp C, Panteghini M
Clin Chem Lab Med. 2008;46(9):1319-25
PMID: 18605952
Trueness verification and traceability assessment of results from commercial systems for measurement of six enzyme activities in serum: an international study in the EC4 framework of the Calibration 2000 project
Jansen R, Schumann G, Baadenhuijsen H, Franck P, Franzini C, Kruse R, Kuypers A, Weykamp C, Panteghini M
Clin Chim Acta. 2006 Jun;368(1-2):160-7
PMID: 16516877
